{"id":591,"date":"2026-09-15T09:03:36","date_gmt":"2026-09-15T06:03:36","guid":{"rendered":"https:\/\/ecomed.kz\/atyrau\/laboratornye-issledovaniya\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/"},"modified":"2026-09-18T11:24:14","modified_gmt":"2026-09-18T08:24:14","slug":"vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases","status":"publish","type":"laboratory_test","link":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/","title":{"rendered":"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases"},"content":{"rendered":"
\n

The Vistara test<\/mark> is a non-invasive prenatal test used to screen the fetus for 25 serious genetic disorders.<\/h2>\n

These disorders can cause skeletal abnormalities, heart defects, multiple congenital anomalies, and\/or intellectual disability.<\/p>\n

General characteristics of the test:<\/strong><\/h2>\n

The test is performed using unique methods based on single nucleotide variants (SNVs), combined with advanced bioinformatics analysis using artificial intelligence.<\/p>\n

\u2014 Vistara\u2122 NIPT includes 25 of the most common autosomal dominant and X-linked dominant disorders involving 30 genes that cause severe skeletal, cardiovascular, and neurological conditions.<\/em><\/p>\n

The monogenic disorders included in the Vistara test have the following characteristics:<\/strong><\/h3>\n
    \n
  • These conditions are difficult or impossible to detect by ultrasound<\/li>\n
  • Other NIPTs do not detect these disorders<\/li>\n
  • Invasive testing does not guarantee an accurate diagnosis<\/li>\n
  • Patient or family history is usually not associated with these mutations, as they typically occur de novo<\/li>\n<\/ul>\n

    Who is recommended to undergo screening for gene mutations:<\/strong><\/h3>\n
      \n
    • Advanced paternal age (if the father is 40 years of age or older)<\/li>\n
    • Pregnant women with ultrasound markers who do not wish to undergo amniocentesis<\/li>\n
    • Individuals with a relevant family history<\/li>\n
    • Patients who wish to obtain as much information as possible<\/li>\n<\/ul>\n

      The test is applicable:<\/strong><\/h3>\n
        \n
      • In singleton pregnancies from 9 weeks of gestation<\/li>\n
      • In pregnancies conceived using a donor egg and in surrogate pregnancies<\/li>\n
      • In cases where the pregnant woman herself does not have a genetic disorder<\/li>\n
      • The fetal fraction threshold used for interpretation of the test results is 4.5%<\/li>\n<\/ul>\n

        Absolute contraindications:<\/strong><\/h2>\n
          \n
        • Pregnancies with more than one fetus, or pregnancies involving fetal demise, vanishing twin, or fetal reduction<\/li>\n
        • Pregnancies with a gestational age of less than 9 weeks<\/li>\n
        • The Vistara test is not recommended if the mother has been diagnosed with a disorder included in the test panel. If the father has been diagnosed with a disorder included in the test panel, the father\u2019s genetic test results must be provided to Natera.<\/li>\n<\/ul>\n

          Limitations of the method:<\/strong><\/h2>\n
            \n
          • Vistara is a screening<\/mark><\/strong> test, meaning that it does not provide a definitive diagnosis<\/strong>.<\/mark> A positive Vistara screening result means that the fetus may be<\/strong><\/mark> affected by the identified disorder. However, screening results alone cannot definitively determine whether the baby has the condition.<\/li>\n
          • The Vistara test is limited to the disorders included in the test panel<\/li>\n<\/ul>\n

            List of conditions tested and corresponding genes<\/strong>:<\/h2>\n
            \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
            Condition<\/strong><\/th>\nGene<\/th>\n<\/tr>\n<\/thead>\n
            Achondroplasia<\/strong><\/td>\n(FGFR3)<\/td>\n<\/tr>\n
            Alagille syndrome<\/strong><\/td>\n(JAG1)<\/td>\n<\/tr>\n
            Antley-Bixler syndrome<\/strong><\/td>\n(FGFR2)<\/td>\n<\/tr>\n
            Apert syndrome<\/strong><\/td>\n(FGFR2)<\/td>\n<\/tr>\n
            Cardiofaciocutaneous syndrome<\/strong><\/td>\n(BRAF, MAP2K1, MAP2K2)<\/td>\n<\/tr>\n
            CATSHL syndrome<\/strong><\/td>\n(FGFR3)<\/td>\n<\/tr>\n
            CHARGE syndrome<\/strong><\/td>\n(CHD7)<\/td>\n<\/tr>\n
            Cornelia de Lange syndrome<\/strong><\/td>\n(NIPBL, SMC1A, SMC3, RAD21, HDAC8)<\/td>\n<\/tr>\n
            Costello syndrome<\/strong><\/td>\n(HRAS)<\/td>\n<\/tr>\n
            Crouzon syndrome<\/strong><\/td>\n(FGFR2, FGFR3)<\/td>\n<\/tr>\n
            Ehlers-Danlos syndrome (classical, cardiac-valvular, types VIIA and VIIB)<\/strong><\/td>\n(COL1A1, COL1A2)<\/td>\n<\/tr>\n
            Early infantile epileptic encephalopathy<\/strong><\/td>\n(CDKL5)<\/td>\n<\/tr>\n
            Hypochondroplasia<\/strong><\/td>\n(FGFR3)<\/td>\n<\/tr>\n
            Intellectual disability<\/strong><\/td>\n(SYNGAP1)<\/td>\n<\/tr>\n
            Jackson-Weiss syndrome<\/strong><\/td>\n(FGFR2)<\/td>\n<\/tr>\n
            Juvenile myelomonocytic leukemia (JMML)<\/strong><\/td>\n\n(PTPN11)<\/td>\n<\/tr>\n
            LEOPARD syndrome (Noonan syndrome with multiple lentigines)<\/strong><\/td>\n(PTPN11, RAF1)<\/td>\n<\/tr>\n
            Muenke syndrome<\/strong><\/td>\n(FGFR3)<\/td>\n<\/tr>\n
            Noonan syndrome<\/strong><\/td>\n(PTPN11, SOS1, RAF1, RIT1, KRAS, NRAS, SOS2, SHOC2, BRAF, MAP2K1, HRAS, CBL)<\/td>\n<\/tr>\n
            Osteogenesis imperfecta (types I, II, III, IV)<\/strong><\/td>\n(COL1A1, COL1A2)<\/td>\n<\/tr>\n
            \nPfeiffer syndrome (types 1, 2, 3)<\/strong><\/td>\n(FGFR2)<\/td>\n<\/tr>\n
            Rett syndrome<\/strong><\/td>\n(MECP2)<\/td>\n<\/tr>\n
            Sotos syndrome<\/strong><\/td>\n(NSD1)<\/td>\n<\/tr>\n
            Thanatophoric dysplasia (types I, II)<\/strong><\/td>\n(FGFR3)<\/td>\n<\/tr>\n
            Tuberous sclerosis (types 1, 2)<\/strong><\/td>\n(TSC1, TSC2)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

            <\/h2>\n

            Required biological material<\/h2>\n

            \n

              \n
            • Maternal venous blood<\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

              The Vistara test is a non-invasive prenatal test used to screen the fetus for 25 serious genetic disorders. These disorders can cause skeletal abnormalities, heart defects, multiple congenital anomalies, and\/or intellectual disability. General characteristics of the test: The test is performed using unique methods based on single nucleotide variants (SNVs), combined with advanced bioinformatics analysis […]<\/p>\n","protected":false},"featured_media":0,"menu_order":0,"template":"","class_list":["post-591","laboratory_test","type-laboratory_test","status-publish","hentry"],"yoast_head":"\nVistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443\" \/>\n<meta property=\"og:description\" content=\"The Vistara test is a non-invasive prenatal test used to screen the fetus for 25 serious genetic disorders. These disorders can cause skeletal abnormalities, heart defects, multiple congenital anomalies, and\/or intellectual disability. General characteristics of the test: The test is performed using unique methods based on single nucleotide variants (SNVs), combined with advanced bioinformatics analysis […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0410\u0442\u044b\u0440\u0430\u0443\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-18T08:24:14+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u041f\u0440\u0438\u043c\u0435\u0440\u043d\u043e\u0435 \u0432\u0440\u0435\u043c\u044f \u0434\u043b\u044f \u0447\u0442\u0435\u043d\u0438\u044f\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 \u043c\u0438\u043d\u0443\u0442\u044b\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/en\\\/laboratory-tests\\\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\\\/\",\"url\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/en\\\/laboratory-tests\\\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\\\/\",\"name\":\"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/#website\"},\"datePublished\":\"2026-09-15T06:03:36+00:00\",\"dateModified\":\"2026-09-18T08:24:14+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/en\\\/laboratory-tests\\\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\\\/#breadcrumb\"},\"inLanguage\":\"ru-RU\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/en\\\/laboratory-tests\\\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/en\\\/laboratory-tests\\\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430\",\"item\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/#website\",\"url\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/\",\"name\":\"\u0410\u0442\u044b\u0440\u0430\u0443\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ecomed.kz\\\/atyrau\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ru-RU\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/","og_locale":"ru_RU","og_type":"article","og_title":"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443","og_description":"The Vistara test is a non-invasive prenatal test used to screen the fetus for 25 serious genetic disorders. These disorders can cause skeletal abnormalities, heart defects, multiple congenital anomalies, and\/or intellectual disability. General characteristics of the test: The test is performed using unique methods based on single nucleotide variants (SNVs), combined with advanced bioinformatics analysis […]","og_url":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/","og_site_name":"\u0410\u0442\u044b\u0440\u0430\u0443","article_modified_time":"2026-09-18T08:24:14+00:00","twitter_card":"summary_large_image","twitter_misc":{"\u041f\u0440\u0438\u043c\u0435\u0440\u043d\u043e\u0435 \u0432\u0440\u0435\u043c\u044f \u0434\u043b\u044f \u0447\u0442\u0435\u043d\u0438\u044f":"3 \u043c\u0438\u043d\u0443\u0442\u044b"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/","url":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/","name":"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases - \u0410\u0442\u044b\u0440\u0430\u0443","isPartOf":{"@id":"https:\/\/ecomed.kz\/atyrau\/#website"},"datePublished":"2026-09-15T06:03:36+00:00","dateModified":"2026-09-18T08:24:14+00:00","breadcrumb":{"@id":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/#breadcrumb"},"inLanguage":"ru-RU","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/ecomed.kz\/atyrau\/en\/laboratory-tests\/vistara-non-invasive-prenatal-screening-test-to-detect-monogenic-fetal-diseases\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430","item":"https:\/\/ecomed.kz\/atyrau\/"},{"@type":"ListItem","position":2,"name":"Vistara Non-invasive prenatal screening test to detect monogenic fetal diseases"}]},{"@type":"WebSite","@id":"https:\/\/ecomed.kz\/atyrau\/#website","url":"https:\/\/ecomed.kz\/atyrau\/","name":"\u0410\u0442\u044b\u0440\u0430\u0443","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ecomed.kz\/atyrau\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ru-RU"}]}},"_links":{"self":[{"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/laboratory_test\/591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/laboratory_test"}],"about":[{"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/types\/laboratory_test"}],"version-history":[{"count":1,"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/laboratory_test\/591\/revisions"}],"predecessor-version":[{"id":1164,"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/laboratory_test\/591\/revisions\/1164"}],"wp:attachment":[{"href":"https:\/\/ecomed.kz\/atyrau\/wp-json\/wp\/v2\/media?parent=591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}