{"id":600,"date":"2026-09-15T07:49:47","date_gmt":"2026-09-15T04:49:47","guid":{"rendered":"https:\/\/ecomed.kz\/shymkent\/laboratornye-issledovaniya\/panorama-neinvazivnyy-prenatalnyy-test-dlya-opredeleniya-rasprostranennyh-hromosomnyh-bolezney-u-ploda-2\/"},"modified":"2026-09-18T11:40:52","modified_gmt":"2026-09-18T08:40:52","slug":"panorama-neinvazivnyy-prenatalnyy-test-dlya-opredeleniya-rasprostranennyh-hromosomnyh-bolezney-u-ploda-2","status":"publish","type":"laboratory_test","link":"https:\/\/ecomed.kz\/shymkent\/en\/laboratory-tests\/panorama-neinvazivnyy-prenatalnyy-test-dlya-opredeleniya-rasprostranennyh-hromosomnyh-bolezney-u-ploda-2\/","title":{"rendered":"Panorama Non-Invasive Prenatal Test for Detecting Common Fetal Chromosomal Abnormalities"},"content":{"rendered":"

What is the PANORAMA TEST<\/strong>?<\/h2>\n

It is a genetic non-invasive prenatal screening test performed using a pregnant woman\u2019s blood that detects common trisomies, aneuploidies, and microdeletions, determines the fetal Rh factor when the mother is Rh-negative, and also includes determination of individual zygosity and fetal fraction in dizygotic twin pregnancies.<\/p>\n

How Panorama\u2122 differs from other existing non-invasive prenatal tests<\/strong><\/h2>\n
    \n
  • Detects deletions as small as 0.5 Mb<\/li>\n
  • Provides highly sensitive screening for 22q11.2 microdeletion<\/li>\n
  • Detects triploidy, complete molar pregnancy, and vanishing twin<\/li>\n
  • Provides highly accurate fetal sex determination<\/li>\n<\/ul>\n

    Explore published scientific studies on the Panorama test<\/strong><\/p>\n

    Conditions under which the test cannot be performed:<\/strong><\/h2>\n
      \n
    • For IVF patients using a donor egg\/surrogacy in combination with a multiple pregnancy<\/u><\/strong>;<\/li>\n
    • Spontaneously conceived pregnancy with an established \u201cvanishing twin\u201d phenomenon (fetal demise), provided that the twins are dizygotic. If the twins are monozygotic and a vanishing twin has been identified, the test can be performed. Note: chorionicity does not determine zygosity.<\/li>\n
    • The minimum fetal fraction after DNA extraction must be 2.8%<\/li>\n
    • In multiple pregnancies involving triplets or more.<\/li>\n
    • In patients with a history of bone marrow or stem cell transplantation.<\/li>\n<\/ul>\n

      The test can be performed from 9 weeks of gestation in an ongoing pregnancy<\/strong>. No special preparation is required for the test.<\/mark><\/h3>\n

      Available testing options<\/strong>:<\/h2>\n
      \n\n\n\n\n\n\n\n\n
      Testing Panels<\/th>\nConditions Screened<\/th>\nOptional<\/th>\nCost<\/th>\n<\/tr>\n<\/thead>\n
      PANORAMA BASIC PANEL<\/strong><\/td>\nDown syndrome, Edwards syndrome, Patau syndrome, triploidy<\/td>\nfetal Rh factor determination + fetal sex determination<\/td>\n<\/td>\n<\/tr>\n
      PANORAMA STANDARD PANEL<\/strong><\/td>\nDown syndrome, Edwards syndrome, Patau syndrome, Turner syndrome, X & Y chromosome abnormalities;<\/td>\nfetal Rh factor determination + fetal sex determination<\/td>\n<\/td>\n<\/tr>\n
      PANORAMA STANDARD PANEL + 22q11.2 DELETION<\/strong><\/td>\nDown syndrome, Edwards syndrome, Patau syndrome, Turner syndrome, X & Y chromosome abnormalities; triploidy; 22q11.2 deletion<\/td>\nfetal Rh factor determination + fetal sex determination<\/td>\n<\/td>\n<\/tr>\n
      PANORAMA EXTENDED PANEL<\/strong><\/td>\nDown syndrome, Edwards syndrome, Patau syndrome, Turner syndrome, X & Y chromosome abnormalities; triploidy; 22q11.2 deletion; fetal sex determination; fetal Rh factor determination; PLUS five microdeletion syndromes: 22q11.2 deletion syndrome, Cri-du-chat syndrome (5p-), 1p36 deletion syndrome, Prader-Willi syndrome (15q11-13), Angelman syndrome (15p-)<\/td>\nfetal Rh factor determination + fetal sex determination<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

      Limitations of the method<\/strong>:<\/h2>\n

      1) Depending on the characteristics of the pregnancy, screening for certain conditions may be subject to limitations. Therefore, consultation with a medical geneticist is required before testing.<\/mark><\/strong><\/p>\n

      2) In rare cases, a sample may not yield a result, and an additional sample may be requested.<\/p>\n

      3) Potential causes of inaccurate results include:<\/p>\n

        \n
      • Mosaicism<\/li>\n
      • Low fetal fraction (fetal DNA)<\/li>\n
      • The test does not detect all possible deletions associated with microdeletion syndromes.<\/li>\n
      • The test has been validated only for complete deletions of the specified loci and may not detect smaller deletions.<\/li>\n
      • The microdeletion risk assessment depends on the fetal fraction because deletions involving the maternally inherited chromosome are more difficult to detect when the fetal fraction is low.<\/li>\n
      • *Fetal Rh factor determination is performed only when the mother is Rh-negative<\/mark><\/strong><\/li>\n<\/ul>\n

        Important! Test results should always be interpreted by a clinician in the context of the patient\u2019s clinical findings and medical history, with subsequent genetic counseling when appropriate.<\/h3>\n

        Required biological material<\/h2>\n

        \n

          \n
        • Maternal venous blood<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

          What is the PANORAMA TEST? It is a genetic non-invasive prenatal screening test performed using a pregnant woman\u2019s blood that detects common trisomies, aneuploidies, and microdeletions, determines the fetal Rh factor when the mother is Rh-negative, and also includes determination of individual zygosity and fetal fraction in dizygotic twin pregnancies. How Panorama\u2122 differs from other […]<\/p>\n","protected":false},"featured_media":0,"menu_order":0,"template":"","class_list":["post-600","laboratory_test","type-laboratory_test","status-publish","hentry"],"yoast_head":"\nPanorama Non-Invasive Prenatal Test for Detecting Common Fetal Chromosomal Abnormalities - \u0428\u044b\u043c\u043a\u0435\u043d\u0442<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ecomed.kz\/shymkent\/en\/laboratory-tests\/panorama-neinvazivnyy-prenatalnyy-test-dlya-opredeleniya-rasprostranennyh-hromosomnyh-bolezney-u-ploda-2\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Panorama Non-Invasive Prenatal Test for Detecting Common Fetal Chromosomal Abnormalities - \u0428\u044b\u043c\u043a\u0435\u043d\u0442\" \/>\n<meta property=\"og:description\" content=\"What is the PANORAMA TEST? It is a genetic non-invasive prenatal screening test performed using a pregnant woman\u2019s blood that detects common trisomies, aneuploidies, and microdeletions, determines the fetal Rh factor when the mother is Rh-negative, and also includes determination of individual zygosity and fetal fraction in dizygotic twin pregnancies. 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