Molecular diagnostic methods play a significant role in the investigation of genetic causes of infertility, enabling the identification of DNA mutations in patients.
Molecular testing is conducted at various stages of bodily development:
• Postnatal diagnostics of children and adults – for establishing or confirming a diagnosis, analyzing the asymptomatic presence of mutations, and identifying genetic predispositions to developing diseases. Material used: peripheral blood leukocytes;
• Preimplantation diagnosis (PGD) – performed to select an embryo that has not inherited a genetic defect from its parents. Material used: embryo blastomeres and cells of the trophectodermal membrane of the embryo.
A geneticist will assist you in determining the necessity and extent of genetic research. You will receive comprehensive information from them regarding the specifics of diagnosing and treating a particular genetic pathology, including preimplantation genetic testing of embryos.
Currently, PGS is the sole test capable of confirming whether an embryo possesses the requisite number of chromosomes before being transferred into the uterine cavity.
PGS reduces the risk of unsuccessful implantation, early miscarriage, and the birth of a child with chromosomal abnormalities, thus increasing the likelihood of a healthy pregnancy.